Dr Fanny Mochel (Sorbonne University; Paris Brain Institute) is a neurologist specialising in neurometabolic disorders and neurogenetics. Her research focuses on inherited metabolic disorders affecting the nervous system, particularly those related to energy metabolism. She has made significant contributions to the understanding of rare neurological disorders and their links to metabolic pathways.Dr Ángeles García-Cazorla (University of Barcelona; Sant Joan de Déu Hospital) is a paediatric neurologist with expertise in neurometabolic and neurodevelopmental disorders. She studies how metabolic imbalances affect brain function, particularly in children with rare neurological disorders. Her work integrates clinical practice and research to improve diagnosis and treatment strategies.Together they have a long history of exploring the complex relationship between metabolism and brain function. Their work in neurometabolic disorders has highlighted the need for a broader, interdisciplinary approach that incorporates fundamental physical principles.Following the success of the first symposium in Barcelona (July 2024), they recognised the growing importance of integrating physics into neurometabolism. Cellular mechanics, energy flow, neurotransmission and even sensory processing all operate according to mechanistic principles that physics can help elucidate.This second symposium in Paris (November 2025) continues its mission to advance our understanding of how physical principles shape brain function and disease by pushing the boundaries of modern neuroscience and neurometabolism, bringing together experts in physics, chemistry, neurobiology and philosophy. It aims to foster interdisciplinary collaboration, generate new hypotheses and develop innovative approaches to the study and treatment of neurometabolic diseases.
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