Transforming Medication Safety in Northern Ireland strategy (TMSNI) was launched by theHealth Minister in September 2020 in response to the World Health Organization’s (WHO) thirdGlobal Patient Safety Challenge ‘Medication without Harm’.The goal of the third Global Patient Safety Challenge on Medication Safety is to gain worldwidecommitment and action to reduce severe, avoidable medication-related harm by 50%, specificallyby addressing harm resulting from errors or unsafe practices due to weaknesses in health systems.