Join 1 upcoming events being held in Santo Domingo Province. Santo Domingo Province, located in the southeastern coast of the Dominican Republic, is a vibrant region filled with rich history, diverse culture, and stunning natural beauty, offering visitors an unforgettable experience with its colonial architecture, pristine beaches, lush national parks, and world-renowned tourist attractions such as the Colonial Zone, Los Tres Ojos National Park, and Boca Chica Beach.