Join 1 upcoming events being held in Issoire. Issoire is a picturesque town in the Puy-de-Dôme department of the Auvergne-Rhône-Alpes region in central France, known for its well-preserved Romanesque architecture, including the stunning Saint-Pierre collegiate church, and its proximity to the scenic Chaine des Puys volcanic range, offering visitors a charming destination to explore history, culture, and natural beauty.